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Buy Euthasol Euthanasia Solution 400mg/ml (250ml) Online Buy Euthasol Euthanasia Solution 400mg/ml (250ml) Online Euthasol Euthanasia Solution 400mg/ml (250ml) Measures should be taken to avoid perivascular administration (e.g. by using intravenous catheter). – The intraperitoneal route of administration may cause a prolonged onset of action with an increased risk of induction excitement. This route of administration is only suitable for small animals. A non-sterile solution containing pentobarbital sodium and phenytoin sodium as the active ingredients. Each mL contains: Active ingredients: 390 mg pentobarbital sodium (barbituric acid derivative), 50 mg phenytoin sodium; Inactive ingredients: 10% ethyl alcohol, 18% propylene glycol, 0.003688 mg rhodamine B, 2% benzyl alcohol (preservative), water for injection q.s. ACTIONS EUTHASOL: Euthasol Euthanasia Solution 400mg/ml (250ml) Solution (pentobarbital sodium and phenytoin sodium) contains two active ingredients which are chemically compatible but pharmacologically different. Each ingredient acts in such a manner so as to cause humane, painless, and rapid euthanasia. Euthanasia is due to cerebral death in conjunction with respiratory arrest and circulatory collapse. Cerebral death occurs prior to the cessation of cardiac activity. When administered intravenously, pentobarbital sodium produces rapid anesthetic action. There is a smooth and rapid onset of unconsciousness. At the lethal dose, there is depression of vital medullary respiratory and vasomotor centers. When administered intravenously, phenytoin sodium produces toxic signs of cardiovascular collapse and/or central nervous system depression. This stage rapidly progresses to deep anesthesia with concomitant reduction in the blood pressure. A few seconds later, breathing stops, due to depression of the medullary respiratory center; encephalographic activity becomes isoelectric, indicating cerebral death; and then cardiac activity ceases. Phenytoin sodium exerts its effect during the deep anesthesia stage caused by the pentobarbital sodium. This ingredient, due to its cardiotoxic properties, hastens the stoppage of electrical activity in the heart. Euthasol Euthanasia Solution Indications For use in dogs for humane, painless, and rapid euthanasia.